No. 6 Indiana travels to Michigan Stadium on Saturday, Oct. 24, 2026, for a Week 8 Big Ten matchup, and the visiting Hoosiers are a touchdown favorite. The Michigan vs Indiana prediction from FOX Sports Research is Indiana -7, with the game set for a 12:00 p.m. ET kickoff on FOX.
Game Details and Betting Lines
The game will be played at Michigan Stadium in Ann Arbor, Mich. It airs on FOX and can be streamed on FOX One, FOXSports.com and the FOX Sports App. Odds from FanDuel Sportsbook, listed as of Oct. 24, make Indiana a -285 favorite on the moneyline. Michigan is +230. The Hoosiers are -7 at -108 on the spread, while the Wolverines are +7 at -112. The over/under is 41.5 at -110 on both sides.
Why Indiana Is Favored
Indiana’s defense has been the story of its season. The Hoosiers lead the Big Ten in scoring defense (12.9 points per game), rushing defense (75.4 yards per game), sacks (24) and tackles for loss (55). They held Ohio State to 19 points and 313 total yards. That defensive profile is a difficult matchup for a Michigan offense that has scored 21 points or fewer in five of six games and averages 17.0 points against Power Four opponents.
Turnovers add another layer. Michigan is tied for the Big Ten lead with 11 giveaways, while Indiana has committed just three. The Hoosiers have won 22 of their last 23 games overall, and under coach Curt Cignetti they are 27-0 against unranked opponents. Indiana is also 2-0 following a loss under Cignetti, with a 66-point win over Purdue and a 13-point win over Old Dominion in those spots.
Quarterback
Indiana’s Josh Hoover has thrown 18 touchdown passes without an interception this season. Michigan could turn to true freshman Tommy Carr for his first career start. If Carr starts, he would face a Top 10 opponent in his debut. True freshman quarterbacks have lost their last 10 first career starts against Top 10 teams, combining for two touchdown passes and 11 interceptions in those games.
The Pick
FOX Sports Research favors Indiana -7. The combination of Indiana’s Big Ten-leading defense, Michigan’s scoring and turnover problems, and the quarterback uncertainty on the Michigan side supports the pick. The Hoosiers’ 27-0 record against unranked opponents under Cignetti and their 2-0 mark after losses add to the case. Kickoff is set for noon ET on FOX.
Odds are from FanDuel Sportsbook and are subject to change. This page may contain affiliate links to legal sports betting partners, and FOX Sports may be compensated for sign-ups or wagers.
